Fast Facts: Comprehensive Genomic Profiling (EPUB)

By Rapoport, Bernardo L., Troncone, Giancarlo, Schmitt, Fernando, Nayler, Simon
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. ‘Fast Facts: Comprehensive Genomic Profiling’ provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: •Genetic mutations and biomarkers •Understanding next-generation sequencing •Elements of comprehensive genomic profiles •Role in precision oncology •Predictive and prognostic biomarkers •Overcoming barriers to genotype-directed therapy

Product Details

• Publisher ‏ : ‎ S. Karger Publishing; 1st edition (October 20, 2020)
• Language ‏ : ‎ English
• Paperback ‏ : ‎ 108 pages
• ISBN-10 ‏ : ‎ 3318068187
• ISBN-13 ‏ : ‎ 978-3318068184