INBBC 2025 16th International Newborn Brain Conference
February 19th – 21st, 2025
La Jolla, San Diego – California
The International Newborn Brain Conference (INBBC) provides a state-of-the-art forum for presentation and discussion of current research and clinical practice in newborn brain care, including diagnosis, monitoring and management strategies to optimize neurodevelopmental outcome. It explores the means to understand, monitor, protect and treat the newborn brain. The INBBC provides continuing medical education to multidisciplinary professionals working to improve the neurological and developmental health outcomes of premature and high-risk newborns.
Main Topics
- Fetal Neuroprotection
- Parent Counselling
- Artificial Intelligence in Neurocritical Care
- Neuroimaging
- Neonatal Seizures
- Neuromonitoring
- Neuromuscular Diseases
- Quality Improvement
- Neuroplasticity and Rehabilitation
- Hot Topics in Neonatal Neurology
Scientific Programme
| Wednesday, February 19 | Thursday, February 20 | Friday, February 21 |
|
07:00 – 08:30 |
07:00 – 08:00 |
07:00 – 08:00 |
| Registration opens (workshop only) | Registration open | Registration open |
| Regency Foyer C | Regency Foyer C | Breakfast |
|
07:00 – 08:30 |
07:00 – 08:00 |
SHOR |
| Breakfast (served for Workshop participants only) | Breakfast |
08:00 – 09:30 |
| La Jolla Ballroom | La Jolla Ballroom | Platform Session 4: Neonatal Seizures: From basic science to new therapies |
| *The Terrace | *La Jolla Garden |
Moderators: Adam Numis, Lena Hellstrom Westas |
| *La Jolla Garden |
07:00 – 08:00 |
08:00 – 08:30 |
|
08:30 – 10:00 |
NBS-TEC Breakfast Mixer (RSVP only) | Basic Science of Seizure Mechanisms and Harm of Seizures |
| Workshops A | The Terrace |
Speaker: Kevin J. Staley |
| 7 parallel workshops (5 in-person, 2 online) |
08:00 – 08:30 |
08:30 – 09:00 |
|
08:30 – 10:00 |
Platform Session 2: AI in Neonatal Neurocritical Care | Seizure Burden – How Best to Measure |
| CUS – Hands on Simulation |
Moderators : Gabriel Variane, Janet Soul |
Speaker: Courtney Wusthoff |
|
Speakers: Khorshid Mohammed, Sylke Steggerde, Lara Leijser |
08:00 – 08:30 |
09:00 – 09:30 |
| Encinitas room | AI and Big Data in Neonatal Neurocritical Care | Current and Future Medications for Neonatal Seizures: Challenges and Opportunities |
|
08:30 – 10:00 |
Speaker: Alvaro Moreira |
Janet Soul |
| Basics of Quality Improvement Part A |
08:30 – 09:00 |
09:30 – 10:15 |
|
Speakers: Jehier Afifi, Bharati Sinha, Tetyana Nesterenko |
AI and Neurophysiology | Coffee Break (AM) |
| Del Mar room |
Speaker: Sampsa Vanhatalo |
Regency Foyer C |
|
08:30 – 10:00 |
09:00 – 09:30 |
10:15 – 11:45 |
| Common Fetal Consults | AI and Neuroimaging in Neurocritical Care | Abstract platform presentations 2 |
|
Speakers: Janet Soul, Sarah Mulkey |
Speaker: Ellen Grant |
Moderators: Pia Wintermark, Christopher Elitt |
| Regency AB |
09:30 – 10:15 |
1. Neurodevelopmental outcomes of normocephalic Colombian children with antenatal Zika virus exposure at school age |
|
08:30 – 10:00 |
Coffee Break (AM) |
Sarah Mulkey |
| Neuroimaging in Term Neonates | Regency Foyer C | 2. Dysregulated Fatty Acid Metabolism Following Neonatal Brain Injury is Rescued by Treatment with Acetate |
|
Speakers: Linda de Vries, Sonia Bonifacio |
10:15 – 11:45 |
Joseph Scafidi |
| Solana Beach room | Platform Session 3: Rare Neuromuscular Disorders: Emerging Gene/Precision Therapies | 3. Telehealth Hammersmith Infant Neurologic Exam supports early diagnosis of cerebral palsy |
|
08:30 – 10:00 |
Moderators: Betsy Ostrander, Ulrike Mietzsch |
Jennifer Keene |
| NIRS Basics and Clinical Applications |
10:15 – 10:45 |
4. Assessing Neonatal Brain Glymphatic System Development Using DTI-ALPS and Choroid Plexus Volume |
|
Speakers: Valerie Chock, Mohamed El-Dib |
Metabolic Myopathies in Newborns |
Ting Peng |
| Regency C |
Speaker: Walla Al-Hertani |
5. Automated EEG background in a multicenter cohort of neonates with hypoxic-ischemic encephalopathy and neurodevelopmental outcomes. |
|
08:30 – 10:00 |
10:45 – 11:15 |
Marie Cornet |
| Neuroimaging in Preterm | Spinal Muscular Atrophy | 6. Perinatal Arterial Stroke treated with Stromal cells IntraNasally (PASSIoN) trial: two-year safety and neurodevelopmental outcome |
|
Speakers: Terrie Inder, Christopher Smyser |
Speaker: Perry Shieh |
Lisanne M. Baak |
| Boardroom |
11:15 – 11:45 |
7. MRI Score and EEG for Two-Year Outcome Prediction: A Secondary Analysis of the ANSeR Studies |
|
08:30 – 10:00 |
Neonatal-onset Myopathies and Dystrophies |
Anne Murray |
| aEEG & cEEG Basics |
Speaker: Carsten G. Bönnemann |
8. Early Machine-Learning Based Quantitative EEG Correlates to Extent of MRI Brain Injury in Neonatal Encephalopathy |
|
Speakers: Geraldine Boylan, Lena Hellstrom-Westas |
11:45 – 13:30 |
Huzaifah Shamim |
| Cardiff | Lunch | 9. Reduced Amygdala Volumes at 6-8 Years in Children Cooled for HIE: Associations With Socioemotional Outcomes |
|
10:00 – 10:30 |
(At leisure, not provided by the conference) |
Sara Rapuc |
| Coffee Break (AM Break) |
12:00 – 13:20 |
11:45 – 13:30 |
| Regency Foyer C | Building long-term follow-up guidelines for HIE: A multidisciplinary workshop hosted by Hope for HIE (RSVP only) | Lunch |
|
10:30 – 12:00 |
La Jolla Ballroom | (At leisure, not provided by the conference) |
| Workshops B |
13:30 – 15:00 |
13:30 – 15:00 |
| 7 parallel workshops (5 in-person, 2 online) | Abstract platform presentations 1 | Hot Topic Symposia |
|
10:30 – 12:00 |
Moderators: Diane Wilson, Hannah Glass |
Moderators: Emily Herzberg, John Barks |
| CUS – Hands on Simulation | 1. Sleep-Disordered Breathing Among Newborns with Fetal vs. Postnatal Myelomeningocele Closure |
13:30 – 14:00 |
|
Speakers: Khorshid Mohammed, Sylke Steggerde, Lara Leijser |
John Barks |
WES and WGS in Neonates |
| Encinitas room | 2. Temporal Analysis of Neonatal SpO2 Patterns Using AI Reveals Early Predictive Signatures of Severe IVH |
Speaker: Pankaj Agrawal |
|
10:30 – 12:00 |
Zachary Vesoulis |
14:00 – 14:30 |
| Basics of Quality Improvement Part B | 3. Association between trajectories of autonomic cardiorespiratory maturation and brain volumetric growth in preterm infants | Fetal Diagnosis and Intervention for Vascular Malformations |
|
Speakers: Jehier Afifi, Bharati Sinha, Tetyana Nesterenko |
Julius Ngwa |
Speaker: Darren Orbach |
| Del Mar room | 4. Neonatal sleep physiology and early executive functioning in children born preterm |
14:30 – 15:00 |
|
10:30 – 12:00 |
Anneleen Dereymaeker |
Novel Fetal Neuroimaging and Therapies |
| Straight talk: hard conversations in the NICU | 5. Predicting neurodevelopmental outcomes in infants with spina bifida myelomeningocele |
Speaker: Ellen Grant |
|
Speakers: Lauren Treat, Betsy Pilon |
Pei-Yi Lin |
15:00 – 15:45 |
| Ocean Beach 1&2 | 6. Maternal immune activation and hypoxia induce neuronal mitochondrial injury preventing cell-cycle exit, arresting cerebellar development | Coffee Break (PM) |
|
10:30 – 12:00 |
Gabriele Simonti |
Regency Foyer C |
| Neuroimaging in Term Neonates | 7. The NutriBrain trial: Can probiotics, prebiotics and glutamine support white matter development in preterm infants? |
15:45 – 17:15 |
|
Speakers: Linda de Vries, Sonia Bonifacio |
Els Janson |
Platform Session 5: Rehabilitation for Children with or at Risk for Hemiparetic CP |
| Boardroom | 8. Melatonin as a neuroprotective strategy in preterm infants: antioxidant properties, neurological outcomes and MRI findings |
Moderators: Alexandra Santana Almansa, Santina Zanelli |
|
10:30 – 12:00 |
Cecilia Naboni |
15:45 – 16:15 |
| NIRS Basics and Clinical Applications | 9. Blood-brain barrier disruption and fibrinogen deposition in the embryonic brain after maternal immune activation | Early Diagnosis of Cerebral Palsy |
|
Speakers: Valerie Chock, Mohamed El-Dib |
Martin Grana |
Speaker: Betsy Ostrander |
| Cardiff |
15:00 – 15:45 |
16:15 – 16:45 |
|
10:30 – 12:00 |
Coffee Break (PM) | Principles of Rehabilitation After Neonatal Brain Injury/Constraint and Other Infant Rehab Therapies |
| Neuroimaging in Preterm | Regency Foyer C |
Speaker: Iona Novak |
|
Speakers: Terrie Inder, Christopher Smyser |
15:45 – 16:45 |
16:45 – 17:15 |
| Regency C | Small Group Discussions 1 | Brain computer interfaces to enable life participation for children after perinatal brain injury. |
|
10:30 – 12:00 |
15:45 – 16:45 |
Speaker: Adam Kirton |
| EEG and Seizures – Clinical Videos & Practical Treatment | Developmental Care During TH |
17:15 – 17:30 |
|
Speakers: Janet Soul, Courtney Wusthoff |
Speakers: Diane Wilson, Mary Anne Ryan |
Closing Remarks |
| Regency AB | Regency AB | |
|
12:00 – 13:45 |
15:45 – 16:45 |
|
| Lunch Break | IVH & PHH Prevention and Management | |
| (At leisure, not provided by the conference) |
Speakers: Mohamed El Dib, Linda de Vries |
|
|
13:45 – 14:00 |
Cardiff | |
| Opening Remarks |
15:45 – 16:45 |
|
|
14:00 – 15:30 |
Management During HIE | |
| Platform Session 1: Fetal Neuroprotection: Understanding Pathophysiology, Risk Factors and Antenatal Therapies |
Speakers: Sonia Bonifacio, Hannah Glass |
|
|
Moderators: Sarah Mulkey, Bharati Sinha |
Solana Beach room | |
|
14:00 – 14:30 |
15:45 – 16:45 |
|
| Neuroplacentology | Neonatal Neurocritical Care Training | |
|
Speaker: Anna Penn |
Speakers: Khorshid Mohammad, Chris Smyser |
|
|
14:30 – 15:00 |
Boardroom | |
| Chorioamnionitis – Animal Models – |
15:45 – 16:45 |
|
|
Speaker: Henrik Hagberg |
Working with Industry | |
|
15:00 – 15:30 |
Speakers: Geraldine Boylan, Betsy Pilon, Terrie Inder |
|
| Antenatal Neuroprotection – Steroids, Mg, etc | Regency C | |
|
Speaker: Bridget Ostrem |
15:45 – 16:45 |
|
|
15:30 – 16:00 |
Connecting Families to Resources | |
| Break |
Speakers: Monica Lemmon, Lauren Treat |
|
|
16:00 – 19:00 |
Encinitas | |
| Reception and Poster Walk |
16:45 – 17:45 |
|
| La Jolla Ballroom | Small Group Discussions 2 | |
|
16:45 – 17:45 |
||
| Developmental Care During TH | ||
|
Speakers: Diane Wilson, Mary Anne Ryan |
||
| Regency AB | ||
|
16:45 – 17:45 |
||
| IVH & PHH Prevention and Management | ||
|
Speakers: Mohamed El Dib, Linda de Vries |
||
| Regency C | ||
|
16:45 – 17:45 |
||
| Management During HIE | ||
|
Speakers: Sonia Bonifacio, Hannah Glass |
||
| Cardiff | ||
|
16:45 – 17:45 |
||
| Neonatal Neurocritical Care Training | ||
|
Speakers: Khorshid Mohammad, Chris Smyser |
||
| Solana Beach room | ||
|
16:45 – 17:45 |
||
| Working with Industry | ||
|
Speakers: Geraldine Boylan, Betsy Pilon, Terrie Inder |
||
| Boardroom | ||
|
16:45 – 17:45 |
||
| Connecting Families to Resources | ||
|
Speakers: Monica Lemmon, Lauren Treat |
||
| Encinitas |
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