Neural Surface Antigens: From Basic Biology Towards Biomedical Applications

by Jan Pruszak

Neural Stem Cells: From Basic Biology Towards Biomedical Applications, edited by Jan Pruszak, M.D., focuses on neural stem cell biology and functional studies in human and mouse models which have significance in translational science. With emphasis on the functional aspects of stem cells and biomarker expression at various stages of development, this reference outlines the role of stem cells in neurogenesis and neural development. It also explores the role of stem cells in biomarker and surface antigen discoveries, which enable scientists to characterize, define and potentially isolate subpopulations of interest for biomedical investigation. Authors from various labs provide a view into the basic biology and functional mechanisms of various molecules, which influence mammalian development, regeneration, and treatments.

• Introduces early phase clinical trials of neural stem cells
• Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics
• Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications

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