Oral Bioavailability and Drug Delivery (Original PDF from Publisher)

<b>ORAL BIOAVAILABILITY <small>AND</small> DRUG DELIVERY</b> <p><b>Improve the performance and viability of newly-developed and approved drugs with this crucial guide</b> <p>Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. <p><i>Oral Bioavailability and Drug Delivery</i> provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. <p><i>Oral Bioavailability and Drug Delivery</i> readers will also find: <ul><li>Discussion questions in many chapters to facilitate comprehension</li> <li>Detailed discussion of topics including dissolution, absorption, metabolism, and more</li> <li>Real-world examples of methods in actions throughout</li></ul> <p><i>Oral Bioavailability and Drug Delivery</i> is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.